National Cancer Institute
U.S. National Institute of Health www.cancer.gov National Cancer Institute
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FEATURED CENTER

 
H. Lee Moffitt Cancer Center & Research Institute

H. Lee Moffitt Cancer Center & Research Institute
H. Lee Moffitt Cancer Center & Research Institute Physical Sciences-Oncology Center's (MCC PS-OC) mission is to assemble a multi-disciplinary group of scientists to incorporate physical science concepts into cancer biology and oncology. Cancer progression can be categorized into several stages defined by markedly diverse temporal and spatial scales - carcinogenesis, invasive cancer, and clinical therapy. Each of these phases of cancer will be explored by this center. In particular, in the investigation of carcinogenesis, these investigators propose that both genetic alterations and microenvironmental selection pressures must be deciphered to impede somatic evolution. Furthermore, this group of prominent theoreticians, cancer biologists and clinicians will apply mathematical modeling to determine if oncogenesis is regulated by the escape from tissue homeostasis, a fresh perspective on the unfolding of cancer. These investigators have a long history of expertly drawing on mathematical modeling to shed light on a variety of complex biological problems in cancer and should provide further insight into the complex problems associated with cancer.
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CENTERS

 
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Physical Science-Oncology Centers

The National Cancer Institute (NCI) has awarded cooperative agreements to 12 leading institutions to build a collaborative network of Physical Science-Oncology Centers (PS-OCs).

 

PHYSICAL SCIENCES-ONCOLOGY CENTERS

 
Arizona State University Arizona State University
Physical Sciences-Oncology Center
Arizona State University, Tempe, AZ

Principal Investigator: Paul Davies, Ph.D.
Scientific Investigator: William M. Grady, M.D.
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Dana-Farber Cancer Institute Dana-Farber Cancer Institute
Physical Sciences-Oncology Center
Dana-Farber Cancer Institute, Boston, MA

Principal Investigator: Franziska Michor, Ph.D.
Scientific Investigator: Eric C. Holland, M.D., Ph.D.
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Johns Hopkins University Johns Hopkins University
Physical Sciences-Oncology Center
Johns Hopkins University, Baltimore, MD

Principal Investigator: Denis Wirtz, Ph.D.
Scientific Investigator: Gregg L. Semenza, M.D., Ph.D.
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The Methodist Hospital Research Institute The Methodist Hospital Research Institute
Physical Sciences-Oncology Center
The Methodist Hospital Research Institute, Houston, TX

Principal Investigator: Mauro Ferrari, Ph.D.
Scientific Investigator: Steven A. Curley, M.D.
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Princeton University Princeton University
Physical Sciences-Oncology Center
Princeton University, Princeton, NJ

Principal Investigator: Robert H. Austin, Ph.D.
Scientific Investigator: Thea D. Tlsty, Ph.D.
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Stanford University Stanford University
Physical Sciences-Oncology Center
Stanford University, Palo Alto, CA

Principal Investigator: Jan Liphardt, Ph.D.
Scientific Investigator: Valerie M. Weaver, Ph.D.
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Cornell University Cornell University
Physical Sciences-Oncology Center
Cornell University, Ithaca, NY

Principal Investigator: Michael L. Shuler, Ph.D.
Scientific Investigator: Barbara L. Hempstead, M.D., Ph.D.
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H. Lee Moffitt Cancer Center & Research Institute H. Lee Moffitt Cancer Center & Research Institute
Physical Sciences-Oncology Center
H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL

Principal Investigator: Robert A. Gatenby, M.D.
Scientific Investigator: Robert J. Gillies, Ph.D.
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Massachusetts Institute of Technology Massachusetts Institute of Technology
Physical Sciences-Oncology Center
Massachusetts Institute of Technology, Cambridge, MA

Principal Investigator: Scott Manalis, Ph.D.
Scientific Investigator: Tyler Jacks, Ph.D.
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Northwestern University Northwestern University
Physical Sciences-Oncology Center
Northwestern University, Chicago, IL

Principal Investigator: Thomas V. O'Halloran, Ph.D.
Scientific Investigator: Jonathan D. Licht, M.D.
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The Scripps Research Institute The Scripps Research Institute
Physical Sciences-Oncology Center
The Scripps Research Institute, La Jolla, CA

Principal Investigator: Peter Kuhn, Ph.D.
Scientific Investigator: Kelly J. Bethel, M.D.
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University Of Southern California University Of Southern California
Physical Sciences-Oncology Center
University of Southern California, Los Angeles, CA

Principal Investigator: W. Daniel Hillis, Ph.D.
Scientific Investigator: David B. Agus, M.D.
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